Computational Tools in Biotechnology MCQ Questions & Answers

21.
Identify the character-based method(s) used for the construction of a phylogenetic tree.
P. Maximum parsimony
Q. Neighbor joining
R. Maximum likelihood
S. Bootstrapping

A. Q only

B. P and R only

C. Q and S only

D. S only

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22.
An example of a program for constructing a phylogenetic tree

A. PHYLIN

B. Phrap

C. ProDom

D. PHDsec

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23.
Amino acid sequences of cytochrome c and ribulose 5-phosphate epimerase from 40 organisms were chosen and phylogenetic trees were obtained for each of these two protein families.
Determine the correctness or otherwise of the following Assertion [A] and the Reason [R].
Assertion [A]: The two trees will not be identical.
Reason [R]: The nature and frequency of mutations in the two families are different.

A. Both [A] and [R] are true and [R] is the correct reason for [A]

B. Both [A] and [R] are true but [R] is not the correct reason for [A]

C. Both [A] and [R] are false

D. [A] is false but [R] is true

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24.
Match the items in Group I with an appropriate description in Group II.

Group I Group II

P. UPGMA 1. Protein sequence database

Q. CLUSTAL 2. Phylogenetic analysis

R. SWISS-PROT 3. 3-D structure visualization

S. RasMol 4. Multiple sequence alignment

A. P-4, Q-1, R-2, S-3

B. P-2, Q-4, R-1, S-3

C. P-2, Q-3, R-1, S-4

D. P-2, Q-1, R-4, S-3

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25.
Number of unrooted trees in a phylogeny of five sequences is

A. 3

B. 15

C. 105

D. 945

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26.
Which one of these is a nucleotide sequence data base?

A. TREMBL

B. EMBL

C. SWISS

D. PROSITE

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27.
The term "Flybase" is a . . .

A. Model organism database

B. Biodiversity database

C. Biomolecular database

D. Literature database

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28.
The algorithm for BLAST is based on

A. Dynamic Programming

B. Hidden Markov Model

C. k-tuple analysis

D. Neural Network

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29.
The process in which macromolecules are released out of cells is known as . . .

A. Exocytosis

B. Pinocytosis

C. Phagocytosis

D. Endocytosis

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30.
PDB is a . . .

A. Composite database for sugar

B. Dimensional database for micromolecules

C. Primary database for macromolecules

D. Electrophoresis database

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Group I	Group II
P. UPGMA	1. Protein sequence database
Q. CLUSTAL	2. Phylogenetic analysis
R. SWISS-PROT	3. 3-D structure visualization
S. RasMol	4. Multiple sequence alignment

Computational Tools in Biotechnology MCQ Questions & Answers | Biotechnology

21. Identify the character-based method(s) used for the construction of a phylogenetic tree. P. Maximum parsimony Q. Neighbor joining R. Maximum likelihood S. Bootstrapping

Answer & Solution

22. An example of a program for constructing a phylogenetic tree

Answer & Solution

Answer & Solution

24. Match the items in Group I with an appropriate description in Group II. Group I Group II P. UPGMA 1. Protein sequence database Q. CLUSTAL 2. Phylogenetic analysis R. SWISS-PROT 3. 3-D structure visualization S. RasMol 4. Multiple sequence alignment

Answer & Solution

25. Number of unrooted trees in a phylogeny of five sequences is

Answer & Solution

26. Which one of these is a nucleotide sequence data base?

Answer & Solution

27. The term "Flybase" is a . . .

Answer & Solution

28. The algorithm for BLAST is based on

Answer & Solution

29. The process in which macromolecules are released out of cells is known as . . .

Answer & Solution

30. PDB is a . . .

Answer & Solution

21.
Identify the character-based method(s) used for the construction of a phylogenetic tree.
P. Maximum parsimony
Q. Neighbor joining
R. Maximum likelihood
S. Bootstrapping

22.
An example of a program for constructing a phylogenetic tree

24.
Match the items in Group I with an appropriate description in Group II.

Group I Group II

P. UPGMA 1. Protein sequence database

Q. CLUSTAL 2. Phylogenetic analysis

R. SWISS-PROT 3. 3-D structure visualization

S. RasMol 4. Multiple sequence alignment

25.
Number of unrooted trees in a phylogeny of five sequences is

26.
Which one of these is a nucleotide sequence data base?

27.
The term "Flybase" is a . . .

28.
The algorithm for BLAST is based on

29.
The process in which macromolecules are released out of cells is known as . . .

30.
PDB is a . . .