Computational Tools in Biotechnology MCQ Questions & Answers

31.
For prediction of three-dimensional structure of protein
P. Homology mode tries many possible alignments.
Q. Threading first identifies homologues.
R. Threading evaluates many rough models.
S. Homology modeling optimizes one model.

A. Q, S

B. P, Q

C. R, S

D. Q, R

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32.
Carl Woese used the gene sequence of which one of the following for phylogenetic taxonomy of prokaryotes?

A. A ribosomal RNA of large ribosomal subunit

B. A ribosomal RNA of small ribosomal subunit

C. A ribosomal protein of large ribosomal subunit

D. A ribosomal protein of small ribosomal subunit

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33.
The retrivel and search tool of the NCBI is . . .

A. Sakura

B. Webin

C. Entrez

D. None of these

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34.
Which one of the following is not an algorithm for building phylogenetic trees?

A. Maximum parsimony

B. Neighbor joining

C. Maximum likelihood

D. Bootstrap

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35.
Which one of the following methods is used to test the significance of a predicted phylogeny?

A. Bootstrap

B. Maximum likelihood

C. Maximum parsimony

D. Minimum evolution

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36.
The amino acid substitution matrices in decreasing order of stringency for comparing protein sequences are

A. PAM250, PAM120, PAM100

B. PAM100, PAM120, PAM250

C. PAM250, PAM100, PAM120

D. PAM120, PAM250, PAM100

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37.
Somethong performed on computer or computer simulation is . . .

A. Insilico

B. Silico

C. Invitro

D. All of these

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38.
Proteomics is the study of . . .

A. Set of carbohydrates

B. Set of proteins

C. Set of specific proteins in the cell

D. Set of entire proteins in a cell

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39.
Match the entries in the Group I with the entries in Group II.

Group I Group II

P. Threading 1. Gene duplication

Q. FASTA 2. Fold prediction

R. Profile 3. HMM

S. Paralogs 4. k-tuple

A. P-2, Q-1, R-3, S-4

B. P-2, Q-4, R-3, S-1

C. P-3, Q-4, R-2, S-1

D. P-1, Q-4, R-3, S-2

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40.
Determine the correctness or otherwise of the following Assertion (A) and Reason (R).
Assertion: UPGMA method produces ultrametric tree.
Reason: Sequence alignment is converted into evolutionary distances in UPGMA method.

A. Both (A) and (R) are true and (R) is the correct reason for (A)

B. Both (A) and (R) are true and (R) is not the correct reason for (A)

C. (A) is true but (R) is false

D. (A) is false but (R) is true

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Group I	Group II
P. Threading	1. Gene duplication
Q. FASTA	2. Fold prediction
R. Profile	3. HMM
S. Paralogs	4. k-tuple

Computational Tools in Biotechnology MCQ Questions & Answers | Biotechnology

31. For prediction of three-dimensional structure of protein P. Homology mode tries many possible alignments. Q. Threading first identifies homologues. R. Threading evaluates many rough models. S. Homology modeling optimizes one model.

Answer & Solution

32. Carl Woese used the gene sequence of which one of the following for phylogenetic taxonomy of prokaryotes?

Answer & Solution

33. The retrivel and search tool of the NCBI is . . .

Answer & Solution

34. Which one of the following is not an algorithm for building phylogenetic trees?

Answer & Solution

35. Which one of the following methods is used to test the significance of a predicted phylogeny?

Answer & Solution

36. The amino acid substitution matrices in decreasing order of stringency for comparing protein sequences are

Answer & Solution

37. Somethong performed on computer or computer simulation is . . .

Answer & Solution

38. Proteomics is the study of . . .

Answer & Solution

39. Match the entries in the Group I with the entries in Group II. Group I Group II P. Threading 1. Gene duplication Q. FASTA 2. Fold prediction R. Profile 3. HMM S. Paralogs 4. k-tuple

Answer & Solution

40. Determine the correctness or otherwise of the following Assertion (A) and Reason (R). Assertion: UPGMA method produces ultrametric tree. Reason: Sequence alignment is converted into evolutionary distances in UPGMA method.

Answer & Solution

31.
For prediction of three-dimensional structure of protein
P. Homology mode tries many possible alignments.
Q. Threading first identifies homologues.
R. Threading evaluates many rough models.
S. Homology modeling optimizes one model.

32.
Carl Woese used the gene sequence of which one of the following for phylogenetic taxonomy of prokaryotes?

33.
The retrivel and search tool of the NCBI is . . .

34.
Which one of the following is not an algorithm for building phylogenetic trees?

35.
Which one of the following methods is used to test the significance of a predicted phylogeny?

36.
The amino acid substitution matrices in decreasing order of stringency for comparing protein sequences are

37.
Somethong performed on computer or computer simulation is . . .

38.
Proteomics is the study of . . .

39.
Match the entries in the Group I with the entries in Group II.

Group I Group II

P. Threading 1. Gene duplication

Q. FASTA 2. Fold prediction

R. Profile 3. HMM

S. Paralogs 4. k-tuple

40.
Determine the correctness or otherwise of the following Assertion (A) and Reason (R).
Assertion: UPGMA method produces ultrametric tree.
Reason: Sequence alignment is converted into evolutionary distances in UPGMA method.