41. Protein P becomes functional upon phosphorylation of a serine residue, replacing this serine with . . . . . . . . will result in a phosphomimic mutant of P.
42. The RNA primer synthesized during the replication process in bacteria is removed by
43. A disease is inherited by a child with a probability of $${1 \over 4}$$. In a family with two children, the probability that exactly one sibling is affected by this disease is
44. The term 'protein splicing' refers to
45. Match the terms in Group I with the ploidy in Group II.
Group I
Group II
P. Disome
1. 2n + 1
Q. Monosome
2. 2n - 1
R. Nullisome
3. n - 1
S. Trisome
4. n + 1
| Group I | Group II |
| P. Disome | 1. 2n + 1 |
| Q. Monosome | 2. 2n - 1 |
| R. Nullisome | 3. n - 1 |
| S. Trisome | 4. n + 1 |
46. A dioecious plant has XX sexual genotype for female and XY for male. After double fertilization, what would be the genotype of the embryos and endosperms?
47. An in vitro translation system can synthesize peptides in all three reading frames of the RNA template. When 5' - UCUCUCUC-(UC)n-UCUCUCUC - 3' was used as the template in this in vitro translation system, the synthesized peptides contained 50% each of serine and leucine. When 5' - CCUCCUCCU-(CCU)n-CCUCCU - 3' was used as the template, the synthesized peptides contained 33.3% each of serine, leucine, and proline. Deduce the codon for proline.
48. During protein synthesis, tRNAs are not involved in
49. If the nucleotide composition (%) of a viral genome is A = 10, U = 20, C = 40 and G = 30, which one of the following is this genome?
50. Which set of the following events occurs during the elongation step of translation?
P. Attachment of mRNA with the smaller subunit of ribosome
Q. Loading of correct aminoacyl-tRNA into the A site.
R. Formation of a peptide bond between the amino acyl-tRNA in the A site and the peptide chain that is attached to the peptidyl-tRNA in the P site.
S. Dissociation of the ribosomal subunits.
T. Translocation of peptidyl-tRNA from the A site to the P site of the ribosome.
P. Attachment of mRNA with the smaller subunit of ribosome
Q. Loading of correct aminoacyl-tRNA into the A site.
R. Formation of a peptide bond between the amino acyl-tRNA in the A site and the peptide chain that is attached to the peptidyl-tRNA in the P site.
S. Dissociation of the ribosomal subunits.
T. Translocation of peptidyl-tRNA from the A site to the P site of the ribosome.