Immunology in Biotechnology MCQ Questions & Answers

31.
A humanized antibody is one in which the

A. Heavy and light chains are from human

B. Heavy chain is from human and light chain is from mouse

C. Light chain is from human and heavy chain is from mouse

D. CDRs are from mouse, and the rest is from human

Answer & Solution Discuss in Board Save for Later

32.
Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II.

Group I Group II

P. Hashimoto's disease 1. Brain

Q. Juvenile diabetes 2. Pancreas

R. Multiple sclerosis 3. Skeletal muscle

S. Myasthenia gravis 4. Thyroid

A. P-1, Q-2, R-3, S-4

B. P-3, Q-1, R-2, S-4

C. P-4, Q-2, R-1, S-3

D. P-1, Q-2, R-4, S-3

Answer & Solution Discuss in Board Save for Later

33.
Which one of the following statements is true with regard to processing and presentation of protein antigens?

A. In the class II MHC pathway, protein antigens in the cytosol are processed by proteasomes

B. In the class I MHC pathway, extracellular protein antigens are endocytosed into vesicles and processed

C. In the class I MHC pathway, transporter associated antigen processing (TAP) protein is required for translocating processed peptides generated in the cytosol

D. Invariant chain in endoplasmic reticulum is involved in transport of peptides and loading of class I MHC

Answer & Solution Discuss in Board Save for Later

34.
Which of the following cytokines are endogenous pyrogens?
P. Tumor necrosis factor α
Q. Interleukin 1
R. Transforming growth factor β
S. Interleukin 10

A. P and Q only

B. P and R only

C. R and S only

D. Q and S only

Answer & Solution Discuss in Board Save for Later

35.
B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from

A. Thymus

B. Bone marrow

C. Spleen

D. Liver

Answer & Solution Discuss in Board Save for Later

36.
Which of the following conditions promote the development of human autoimmune disorders?
P. Inability to eliminate self-reactive lymphocytes
Q. Generation of auto-antibodies
R. Ability to eliminate self-reactive T cells
S. Induction of regulatory T cells in the thymus

A. P, R

B. Q. S

C. P, Q

D. R, S

Answer & Solution Discuss in Board Save for Later

37.
Which one of the following is not a principal component of innate immunity?

A. Mucosal epithelia

B. Dendritic cells

C. Complement system

D. Memory B cells

Answer & Solution Discuss in Board Save for Later

38.
A neonatally thymectomized mouse, immunized with protein antigen shows

A. Both primary and secondary responses to the antigen

B. Only primary response to the antigen

C. Delayed type hypersensitive reactions

D. No response to the antigen

Answer & Solution Discuss in Board Save for Later

39.
Which of these mice fall to develop a thymus?

A. Motheaten mice

B. Beige mice

C. Knock out mice

D. Nude mice

Answer & Solution Discuss in Board Save for Later

40.
Abzymes are

A. Enzymes that are highly specific like antibodies

B. Antibodies that have catalytic activities

C. Also, referred to as zymogens

D. Enzymes which hydrolyze antibodies

Answer & Solution Discuss in Board Save for Later

Group I	Group II
P. Hashimoto's disease	1. Brain
Q. Juvenile diabetes	2. Pancreas
R. Multiple sclerosis	3. Skeletal muscle
S. Myasthenia gravis	4. Thyroid

Immunology in Biotechnology MCQ Questions & Answers | Biotechnology

31. A humanized antibody is one in which the

Answer & Solution

32. Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II. Group I Group II P. Hashimoto's disease 1. Brain Q. Juvenile diabetes 2. Pancreas R. Multiple sclerosis 3. Skeletal muscle S. Myasthenia gravis 4. Thyroid

Answer & Solution

33. Which one of the following statements is true with regard to processing and presentation of protein antigens?

Answer & Solution

34. Which of the following cytokines are endogenous pyrogens? P. Tumor necrosis factor α Q. Interleukin 1 R. Transforming growth factor β S. Interleukin 10

Answer & Solution

35. B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from

Answer & Solution

36. Which of the following conditions promote the development of human autoimmune disorders? P. Inability to eliminate self-reactive lymphocytes Q. Generation of auto-antibodies R. Ability to eliminate self-reactive T cells S. Induction of regulatory T cells in the thymus

Answer & Solution

37. Which one of the following is not a principal component of innate immunity?

Answer & Solution

38. A neonatally thymectomized mouse, immunized with protein antigen shows

Answer & Solution

39. Which of these mice fall to develop a thymus?

Answer & Solution

40. Abzymes are

Answer & Solution

31.
A humanized antibody is one in which the

32.
Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II.

Group I Group II

P. Hashimoto's disease 1. Brain

Q. Juvenile diabetes 2. Pancreas

R. Multiple sclerosis 3. Skeletal muscle

S. Myasthenia gravis 4. Thyroid

33.
Which one of the following statements is true with regard to processing and presentation of protein antigens?

34.
Which of the following cytokines are endogenous pyrogens?
P. Tumor necrosis factor α
Q. Interleukin 1
R. Transforming growth factor β
S. Interleukin 10

35.
B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from

36.
Which of the following conditions promote the development of human autoimmune disorders?
P. Inability to eliminate self-reactive lymphocytes
Q. Generation of auto-antibodies
R. Ability to eliminate self-reactive T cells
S. Induction of regulatory T cells in the thymus

37.
Which one of the following is not a principal component of innate immunity?

38.
A neonatally thymectomized mouse, immunized with protein antigen shows

39.
Which of these mice fall to develop a thymus?

40.
Abzymes are