Examveda

'Colchicine' interferes with

A. Replication

B. Recombination

C. Formation of spindle fibres

D. All of these

Answer: Option C

Solution (By Examveda Team)

'Colchicine' interferes with the Formation of spindle fibres.
The alkaloid drug, colchicine, extracted from the corm of the autumn crocus (Colchicum autumnale), arrests mitosis in metaphase by interfering with the formation of spindle fibrils, thereby retarding the division of the centromeres and preventing the division of the centrioles.

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