Examveda

Hayflick limit of mammalian cells refers to which one of the following?

A. Cells in primary cell culture undergo senescence after 50-60 passages

B. Primary cells cultured in vitro do not cross the limit of cell transformation

C. Cell lines when cultured in vitro have a limit for their surface to volume ratio

D. Malignant cell lines undergo senescence after 50-60 passages

Answer: Option A


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Metaplasia represents

A. Uncontrolled proliferation of cells initiated at the metaphase of cell cycle

B. Transformation of one differentiated cell type to another

C. Cell proliferation during metamorphosis

D. A measure of metabolic activity in hyperplastic cells