Hayflick limit of mammalian cells refers to which one of the following?
A. Cells in primary cell culture undergo senescence after 50-60 passages
B. Primary cells cultured in vitro do not cross the limit of cell transformation
C. Cell lines when cultured in vitro have a limit for their surface to volume ratio
D. Malignant cell lines undergo senescence after 50-60 passages
Answer: Option A
Which one of the following changes occurs in a directionally migrating eukaryotic cell?
A. The ER is fragmented
B. The mitochondrial membrane potential drops
C. The nucleus moves towards the back and behind the Golgi
D. The Golgi is fragmented
A. P, Q and S only
B. P, Q and R only
C. Q, R and S only
D. P, R and S only
A. Uncontrolled proliferation of cells initiated at the metaphase of cell cycle
B. Transformation of one differentiated cell type to another
C. Cell proliferation during metamorphosis
D. A measure of metabolic activity in hyperplastic cells
A. Endoplasmic reticulum
B. Golgi
C. Mitochondria
D. Peroxisomes

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