In honey bees, the queen substance is secreted by

In honey bees, the queen substance is secreted by Mandibular glands.
Mandibular glands, found in many insects, function as the main salivary glands in Lepidoptera larvae. A common function of mandibular glands in social Hymenoptera is to produce pheromones such as alarm pheromones in ants and honey bees, and the queen substance in queen honey bees.
The queen pheromone is produced by the queen's mandibular glands and its five known components are 9-oxo-(E)-2-decenoic acid, (+)- and (−)-9-hydroxy (E)-2-decenoic acid, methyl p-hydroxybenzoate, and 4-hydroxy-3-methoxyphenylethanol.