Major health effects due to depletion of ozone layer is/are

Major health effects due to depletion of ozone layer are Increase in eye cataracts and mutation, Increase in skin cancer and melanoma and also a decrease in growth of ocean flora and fauna.
Ozone layer depletion increases surface UVB levels, which could lead to damage, including an increase in skin cancer. The ozone hole was seen as a "hot issue" and imminent risk as laypeople feared severe personal consequences such as skin cancer, cataracts, damage to plants, and reduction of plankton populations in the ocean's photic zone.