The East India Company was founded in India during the reign of

The East India Company, formally known as the British East India Company, was founded in India during the reign of Akbar, the Mughal emperor. The company was established with the aim of conducting trade with the Indian subcontinent and other regions. It was granted a royal charter by Queen Elizabeth I of England in 1600.

During Akbar's reign, the British East India Company began establishing its trading posts and presence in India. Over time, the company's influence grew, leading to significant political and economic developments, eventually culminating in British colonial rule over India.

Therefore, the correct option is Option C: Akbar, during whose reign the East India Company was founded in India.