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The histone proteins which are highly conserved is

A. H1, H2, H3, H4

B. H2a, H2b, H3, H4

C. H1, H3, H4

D. H1, H2a, H2b

Answer: Option B

Solution(By Examveda Team)

The highly conserved histone proteins are H2a, H2b, H3 and H4.
Histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei. They act as spools around which DNA winds to create structural units called nucleosomes.
The 4 'core' histones (H2a, H2b, H3 and H4) are relatively similar in structure and are highly conserved through evolution. They also share the feature of long 'tails' on one end of the amino acid structure - this being the location of a post-translational modification.

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