Examveda

The histones of DNA are synthesized in

A. G1 phase

B. G2 phase

C. S phase

D. G0 phase

Answer: Option C

Solution (By Examveda Team)

The histones of DNA are synthesized in the S phase.
The new histones are made in the cytoplasm during the S phase and are transported into the nucleus. It is deposited by chromatin assembly factors or histone chaperones on replicating DNA to form chromatin in a process known as chromatin assembly.
The old histones are disassembled from DNA, presumably shielded and chaperoned until they are reassembled into nucleosomes.

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