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Which is/are inhibitor of sclerotization

A. MON-0585

B. α-methyl DOPA

C. Dihydroxy Phenyl alanine Decarboxylase (DDC)

D. All of these

Answer: Option D

Solution(By Examveda Team)

The inhibitor of sclerotization is MON-0585, α-methyl DOPA, and Dihydroxy Phenyl alanine Decarboxylase (DDC).
Sclerotization is the process of cuticular hardening which typically occurs within a few hours after each moult, due to the formation of cross-links between catecholamines or other phenolics and the protein and chitin fibrillar components of the cuticular matrix.
α-methyl-DOPA (3,4-dihydroxyphenylalanine) and substituted phenols are suicide substrates for special enzymes here. Cyromazine was discovered by Hall and Foehse (1980) and has good activity on Diptera and Lepidoptera.

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