A bioreactor is scaled up based on equal impeller tip speed. Consider the following parameters for small and large bioreactors:
Parameters | Small bioreactor | Large bioreactor |
Impeller speed | N1 | N2 |
Diameter of impeller | D1 | D2 |
Power consumption | P1 | P2 |
Assuming geometrical similarity and the bioreactors are operated in turbulent regime, what will be $$\frac{{{P_2}}}{{{P_1}}}$$ ?
A. $${\left( {\frac{{{D_1}}}{{{D_2}}}} \right)^2}$$
B. $${\left( {\frac{{{D_2}}}{{{D_1}}}} \right)^2}$$
C. $${\left( {\frac{{{D_1}}}{{{D_2}}}} \right)^5}$$
D. $${\left( {\frac{{{D_2}}}{{{D_1}}}} \right)^5}$$
Answer: Option A
Related Questions on Bioprocess Engineering and Process Biotechnology
Which of the following techniques is best suited for immobilizing an affinity ligand?
A. Physical adsorption
B. Gel entrapment
C. Crosslinking with a polymer
D. Covalent linkage to a spacer arm
Which one of the following can not be a limiting substrate if Monod's growth kinetics is applicable?
A. Extracellular carbon source
B. Extracellular nitrogen source
C. Dissolved oxygen
D. Intracellular carbon source
A. P-2, Q-3, R-1, S-4
B. P-1, Q-2, R-4, S-3
C. P-3, Q-2, R-4, S-1
D. P-3, Q-4, R-2, S-1
A. 10 h
B. 0.2 h
C. 4.6 h
D. None of the above
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