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This question belongs to Competitive English Antonyms
Antonyms
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Antonym of SANCTIFY

Answer & Solution
Correct Answer: Option D
Sanctify : set apart as or declare holy.
Dedicate : devote (time or effort) to a particular task or purpose.
Patronise : treat in a way that is apparently kind or helpful but that betrays a feeling of superiority.
Venerate : regard with great respect; revere.
Pollute : contaminate (water, the air, etc.) with harmful or poisonous substances.

Antonym of Sanctify is Pollute
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