Molecular Biology and Genetics MCQ Questions & Answers

51.
In a genetic cross between the genotypes WWXX and wwxx, the following phenotypic distributions were observed among the F₂ progeny: WX, 562; wx, 158; Wx, 38; and wX, 42. Likewise, a cross between XXYY and xxyy yielded the following results: XY, 675; xy, 175; Xy, 72; and xY, 78. Similarly, a cross between WWYY and wwyy yielded: WY, 292; wy, 88; Wy, 12; and wY, 8. In all the genotypes, capital letters denote the dominant allele. Assume that the F₁ progeny were self-fertilized in all three crosses. Also, double cross-over does not occur in this species. Which of the following is correct?

A. Relative position: W-X-Y Distances: W-X = 5 map units, X-Y = 17 map units

B. Relative position: X-Y-W Distances: X-Y = 15 map units, Y-W = 11 map units

C. Relative position: Y-W-X Distances: Y-W = 5 map units, W-X = 11 map units

D. Relative position: X-W-Y Distances: X-W = 5 map units, W-Y = 10 map units

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52.
The major groove of DNA is lined by

A. N3 of purine and N1 of pyrimidine

B. N7 of purine and O2 of pyrimidine

C. N7 of purine and C4 of pyrimidine

D. None of the above

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53.
An example for template independent DNA polymerase is

A. DNA Polymerase I

B. RNA polymerase

C. Terminal deoxynucleotidyl transferase

D. DNA polymerase III

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54.
Synteny refers to

A. Gene duplication from a common ancestor

B. A tree representation of related sequences

C. The extent of similarity between two sequences

D. Local conservation of gene order

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55.
Which of the following processes can increase genetic diversity of bacteria in nature?
P. Conjugation
Q. Transformation
R. Transduction
S. Transfection

A. P only

B. P and Q only

C. P, Q and R only

D. P, Q, R and S

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56.
"Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: N-methyl-N'-nitro-N-nitrosoguanidine (NTG) is an effective chemical mutagen.
Reason: Mutations induced by NTG mainly are the GC → AT transitions."

A. Both (A) and (R) are true and (R) is the correct reason for (A)

B. Both (A) and (R) are true but (R) is not the correct reason for (A)

C. (A) is true but (R) is false

D. (A) is false but (R) is true

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57.
If a segment of a sense strand of DNA is 5'-ATGGACCAGA-3', then the resulting RNA sequence after transcription is

A. 5'-AGACCAGGTA-3'

B. 5'-UCUGGUCCAU-3'

C. 5'-UACCUGGUCU-3'

D. 5'-AUGGACCAGA-3'

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58.
Which of the following statements with respect to the orientation of the nitrogenous bases to the pentose sugars, and the puckering of the sugar, is correct?

A. Anti, and 2'-endo in A form DNA

B. Anti, and 2'-endo in B form DNA

C. Syn, and 3'-endo in A form DNA

D. Syn, and 3'-endo in B form DNA

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59.
Of the two diploid species, species I has 36 chromosomes and species II has 28 chromosomes. How many chromosomes would be found in an allotriploid individual?

A. 42 or 54

B. 46 or 50

C. 74 or 86

D. 84 or 108

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60.
Ames test is used to determine

A. The mutagenicity of a chemical

B. Carcinogenicity of a chemical

C. Both mutagenicity and carcinogenicity of a chemical

D. Toxicity of a chemical

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Molecular Biology and Genetics MCQ Questions & Answers | Biotechnology

Answer & Solution

52. The major groove of DNA is lined by

Answer & Solution

53. An example for template independent DNA polymerase is

Answer & Solution

54. Synteny refers to

Answer & Solution

55. Which of the following processes can increase genetic diversity of bacteria in nature? P. Conjugation Q. Transformation R. Transduction S. Transfection

Answer & Solution

56. "Determine the correctness or otherwise of the following Assertion (A) and the Reason (R). Assertion: N-methyl-N'-nitro-N-nitrosoguanidine (NTG) is an effective chemical mutagen. Reason: Mutations induced by NTG mainly are the GC → AT transitions."

Answer & Solution

57. If a segment of a sense strand of DNA is 5'-ATGGACCAGA-3', then the resulting RNA sequence after transcription is

Answer & Solution

58. Which of the following statements with respect to the orientation of the nitrogenous bases to the pentose sugars, and the puckering of the sugar, is correct?

Answer & Solution

59. Of the two diploid species, species I has 36 chromosomes and species II has 28 chromosomes. How many chromosomes would be found in an allotriploid individual?

Answer & Solution

60. Ames test is used to determine

Answer & Solution

52.
The major groove of DNA is lined by

53.
An example for template independent DNA polymerase is

54.
Synteny refers to

55.
Which of the following processes can increase genetic diversity of bacteria in nature?
P. Conjugation
Q. Transformation
R. Transduction
S. Transfection

56.
"Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: N-methyl-N'-nitro-N-nitrosoguanidine (NTG) is an effective chemical mutagen.
Reason: Mutations induced by NTG mainly are the GC → AT transitions."

57.
If a segment of a sense strand of DNA is 5'-ATGGACCAGA-3', then the resulting RNA sequence after transcription is

58.
Which of the following statements with respect to the orientation of the nitrogenous bases to the pentose sugars, and the puckering of the sugar, is correct?

59.
Of the two diploid species, species I has 36 chromosomes and species II has 28 chromosomes. How many chromosomes would be found in an allotriploid individual?

60.
Ames test is used to determine