Cells deficient in hypoxanthine guanine phospho-ribosyl transferase (HGPRT)
A. Synthesis of purine deoxynucleotides by salvage pathway
B. Synthesis of purine deoxynucleotides by de novo path way
C. Supply of hypoxanthine in the culture medium
D. Supply of thymidine in the culture medium enzyme rely on
Answer: Option B
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