Rate limiting enzyme in cholesterol biosynthesis
A. α 1-4 glucosidase
B. HMG-CoA reductase
C. Squalene synthetase
D. 7 α-hydroxylase
Answer: Option B
Solution (By Examveda Team)
Rate limiting enzyme in cholesterol biosynthesis is HMG-CoA reductase.The biosynthetic pathway of cholesterol proceeds through several intermediates and involves different enzymes.
The rate-limiting step of cholesterol synthesis is the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase that synthesizes mevalonate starting from HMG-CoA.
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