Such lofty dreams can never come true.

A. puny

B. humble

C. insignificant

D. casual

Answer: Option B

Solution(By Examveda Team)

Lofty :proud; arrogant.
Puny : small and weak.
Humble : having or showing a modest or low estimate of one's importance.
Insignificant : too small or unimportant to be worth consideration.
Casual : relaxed and unconcerned.

Antonym of Lofty is Humble