Which NSAIDs drug is a selective cox-2 inhibitor ?

Solution (By Examveda Team)

The correct answer is Option C: Etoricoxib
Let's break down why:
NSAIDs stand for Non-Steroidal Anti-Inflammatory Drugs.
These drugs work by blocking enzymes called COX (Cyclooxygenase) enzymes.
There are two main types of COX enzymes: COX-1 and COX-2.
COX-1 is important for protecting the stomach lining and other bodily functions.
COX-2 is mainly involved in inflammation and pain.
Selective COX-2 inhibitors target COX-2 specifically, with the goal of reducing pain and inflammation while minimizing side effects on the stomach.
Now, let's look at the options:
Option A: Endomethacin is not a selective COX-2 inhibitor. It inhibits both COX-1 and COX-2.
Option B: Meloxicam has some selectivity for COX-2 but is not considered a highly selective inhibitor like Etoricoxib.
Option C: Etoricoxib is a highly selective COX-2 inhibitor.
Option D: Mefenamic acid is a non-selective NSAID and inhibits both COX-1 and COX-2.
Therefore, Etoricoxib is the only option that is a selective COX-2 inhibitor.