Computational Tools in Biotechnology MCQ Questions & Answers

1.
The method used for prediction of three-dimensional structure of a protein from known structure(s) of one or more related proteins is

A. Multiple sequence alignment

B. Homology modeling

C. Phylogeny

D. Docking

Answer & Solution Discuss in Board Save for Later

2.
Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database?

A. Blastp

B. Blastn

C. Blastx

D. Tblastn

Answer & Solution Discuss in Board Save for Later

3.
The multiple sequence alignment tool is . . .

A. Clastal W

B. SCOP

C. Gene bank

D. All of these

Answer & Solution Discuss in Board Save for Later

4.
How many rooted and unrooted phylogenetic trees, respectively, are possible with four different sequences?

A. 3 and 15

B. 15 and 3

C. 15 and 12

D. 12 and 3

Answer & Solution Discuss in Board Save for Later

5.
Identify the file format given below:
>P1; JMFD
Protein X - Homo sapiens
MKALT ARQQEVFDLIRDHISRTLRQQGDWL

A. GDE

B. FASTA

C. NBRF

D. GCG

Answer & Solution Discuss in Board Save for Later

6.
The compound that has properties to become a drug is known as . . .

A. Fit drug

B. Fit compound

C. Lead

D. Find drug

Answer & Solution Discuss in Board Save for Later

7.
Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?

A. BLASTN

B. BLASTX

C. TBLASTN

D. TBLASTX

Answer & Solution Discuss in Board Save for Later

8.
In bioinformatics, the term 'BLAST' refers to

A. Database retrieval tool

B. Computational tool for sequence homology searching and alignment

C. Computational tool to view genomic sequences

D. Computational tool to view protein structures

Answer & Solution Discuss in Board Save for Later

9.
Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Ab initio gene finding algorithms that predict protein coding genes in eukaryotic genomes are not completely accurate.
Reason: Eukaryotic splice sites are difficult to predict.

A. Both (A) and (R) are false

B. (A) is true but (R) is false

C. Both (A) and (R) are true and (R) is the correct reason for (A)

D. Both (A) and (R) are true but (R) is not the correct reason for (A)

Answer & Solution Discuss in Board Save for Later

10.
While searching a database for similar sequences, E-value does not depend on the

A. Sequence length

B. Number of sequences in the database

C. Scoring system

D. Probability from a normal distribution

Answer & Solution Discuss in Board Save for Later

Computational Tools in Biotechnology MCQ Questions & Answers | Biotechnology

1. The method used for prediction of three-dimensional structure of a protein from known structure(s) of one or more related proteins is

Answer & Solution

2. Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database?

Answer & Solution

3. The multiple sequence alignment tool is . . .

Answer & Solution

4. How many rooted and unrooted phylogenetic trees, respectively, are possible with four different sequences?

Answer & Solution

5. Identify the file format given below: >P1; JMFD Protein X - Homo sapiens MKALT ARQQEVFDLIRDHISRTLRQQGDWL

Answer & Solution

6. The compound that has properties to become a drug is known as . . .

Answer & Solution

7. Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?

Answer & Solution

8. In bioinformatics, the term 'BLAST' refers to

Answer & Solution

9. Determine the correctness or otherwise of the following Assertion (A) and the Reason (R). Assertion: Ab initio gene finding algorithms that predict protein coding genes in eukaryotic genomes are not completely accurate. Reason: Eukaryotic splice sites are difficult to predict.

Answer & Solution

10. While searching a database for similar sequences, E-value does not depend on the

Answer & Solution

1.
The method used for prediction of three-dimensional structure of a protein from known structure(s) of one or more related proteins is

2.
Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database?

3.
The multiple sequence alignment tool is . . .

4.
How many rooted and unrooted phylogenetic trees, respectively, are possible with four different sequences?

5.
Identify the file format given below:
>P1; JMFD
Protein X - Homo sapiens
MKALT ARQQEVFDLIRDHISRTLRQQGDWL

6.
The compound that has properties to become a drug is known as . . .

7.
Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?

8.
In bioinformatics, the term 'BLAST' refers to

9.
Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Ab initio gene finding algorithms that predict protein coding genes in eukaryotic genomes are not completely accurate.
Reason: Eukaryotic splice sites are difficult to predict.

10.
While searching a database for similar sequences, E-value does not depend on the