1
The precursor for penicillin-G biosynthesis during fermentation process is
A)
Phenylacetic acid
B)
Phenoxyacetic acid
C)
Acetic acid
D)
None of the above
Answer & Solution
Answer: Option
A
2
Which of the following eukaryotic organisms has been proven to be of great industrial importance?
A)
Penicillium chrysogenum
B)
Saccharomyces cerevisiae
C)
Bacillus subtilis
D)
Streptomyces griseus
Answer & Solution
Answer: Option
B
3
Oils rich in PUFA are not desirable for biodiesel production because
A)
They form epoxides in presence of oxygen
B)
They do not form epoxides in presence of oxygen
C)
They have high ignition temperature
D)
They solidify at low temperature
Answer & Solution
Answer: Option
A
4
Match the products in
Group I with their ppossible applications in
Group II .
Group I Group II
P. Erythropoietin
1. Blood clot
Q. Anti-fibrin 99
2. Binding and transport of iron
R. Collagenase
3. Anaemia
S. S. Transferrin
4. Animal cell separation
A)
P-3, Q-1, R-4, S-2
B)
P-3, Q-4, R-1, S-2
C)
P-2, Q-3, R-1, S-4
D)
P-2, Q-1, R-4, S-3
Answer & Solution
Answer: Option
A
5
Match the recombinant products in
Group I with their therapeutic applications in
Group II .
Group I Group II
P. Human growth hormone
1. Pituitary dwarfism
Q. Platelet growth factor
2. Chemotherapy induced thrombocytopenia
R. Factor VIII
3. Hemophilia
S. Erythropoietin
4. Anemia associated with chronic renal failure
A)
P-1, Q-2, R-3, S-4
B)
P-2, Q-1, R-3, S-4
C)
P-1, Q-4, R-3, S-2
D)
P-2, Q-4, R-3, S-1
Answer & Solution
Answer: Option
A
6
Identify the statement that is not correct
A)
Penicillin fermentation is an aerobic process
B)
Penicillin biosynthesis is affected by phosphate concentration
C)
Lysine stimulates penicillin synthesis
D)
Penicillin production shows a distinct catabolite repression by glucose
Answer & Solution
Answer: Option
C
7
Examine the data given below in the table on purification of a protein X.
Step Volume (mL) Protein Concentration (mg mL-1)
Enzyme Activity (unit mL-1 )
Crude cell-free extract
500
12.0
5.0
Ammonium sulfate precipitation
125
3.0
11.0
Ion-exchange chromatography
10
9.0
75.0
The yield percent and purification factor, respectively, at the end of the experiment will be approximately
A)
25 and 3
B)
30 and 20
C)
20 and 30
D)
75 and 30
Answer & Solution
Answer: Option
B
8
Match the activity spectrum of the following antibiotics.
Group I Group II
P. Actinomycin D
1. Antifungal
Q. Daunorubicin
2. Antituberculosis
R. Rifamycin
3. Antitumor
S. Griseofulvin
4. Antiprotozoal
A)
P-3, Q-4, R-2, S-1
B)
P-3, Q-1, R-4, S-2
C)
P-3, Q-1, R-2, S-4
D)
P-2, Q-1, R-4, S-3
Answer & Solution
Answer: Option
A
9
Determine the correctness or otherwise of the following Assertion (A) and Reason (R) .Assertion: Cell mass yield of a methylotrophic yeast is more on methanol compared to glucose.Reason: Methanol has a greater degree of reductance compared to glucose.
A)
Both (A) and (R) are correct and (R) is the correct reason for (A)
B)
(A) is correct, (R) is false
C)
(A) is false, (R) is correct
D)
Both (A) and (R) are correct but (R) is not the correct reason for (A)
Answer & Solution
Answer: Option
A
10
Match the products in
Group I with their producer organisms given in
Group II .
Group I Group II
P. Ethanol
1. Streptomyces orientalis
Q. L-Lysine
2. Saccharomyces cerevisiae
R. Biopesticide
3. Corynebacterium glutanicum
S. Vancomycin
4. Bacillus thuringiensis
A)
P-2, Q-3, R-4, S-1
B)
P-3, Q-4, R-1, S-2
C)
P-4, Q-1, R-2, S-3
D)
P-2, Q-1, R-4, S-3
Answer & Solution
Answer: Option
A
