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One Word Substitution
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A disease which ends in death

Answer & Solution
Correct Answer: Option C
One word substitute is Fatal.

Contagious: (of a disease) spread from one person or organism to another, typically by direct contact.
Harmless: not able or likely to cause harm.
Fatal: causing death.
Safe: protected from or not exposed to danger or risk; not likely to be harmed or lost.
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