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One Word Substitution
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A pioneer of a reform movement:

Answer & Solution
Correct Answer: Option A
The one word substitution is Apostle.

Apothecary : a person who prepared and sold medicines and drugs.
Apotheosis : the highest point in the development of something; a culmination or climax.
Renegade : a person who deserts and betrays an organization, country, or set of principles.
Apostle : a vigorous and pioneering advocate or supporter of a particular policy, idea, or cause.
Examveda
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