Distant hybridization is associated with

Distant hybridization is associated with Hybrid inviability, Hybrid sterility and Hybrid breakdown.
Distant hybridization refers to crosses between two different species, genera, or higher-ranking taxa, which can break species limits, increase genetic variation, and combine the biological characteristics of existing species.
Hybrid inviability is a post-zygotic barrier, which reduces a hybrid's capacity to mature into a healthy, fit adult.
Hybrid sterility is defined as the inhibition or suppression of the reproductive capacity of F1 or later-generation hybrids between genetically different strains or populations, usually belonging to different species.
The hybrid breakdown is a type of reproductive failure that appears after the F2 generation of crosses between different species or subspecies. It is caused by incompatibility between interacting genes.