In Bengal, the East India Company's headquarters were located at

In Bengal, the East India Company's headquarters were located at Fort William. Fort William was a fortified British outpost built in Calcutta (now Kolkata) to establish and maintain control over the British East India Company's trading activities in the region.

Fort William was strategically situated near the Hooghly River and served as a vital center for the administration, trade, and governance of the British East India Company's interests in Bengal. The headquarters played a crucial role in shaping the early colonial history of British presence in India.

Option A: Fort St George is located in Chennai (formerly Madras) and served as the headquarters of the British East India Company's activities in the Madras Presidency.
Option C: Fort St David is located in Cuddalore and was another British outpost in Tamil Nadu.
Option D: Shantiniketan, founded by Rabindranath Tagore, is not related to the East India Company's headquarters.

Therefore, the correct option is Option B: Fort William, which served as the East India Company's headquarters in Bengal.