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Inhibitors to cell membrane synthesis are
Answer & Solution
Correct Answer:
Option
D
Inhibitors to cell membrane synthesis are Polymixin, Gramicidin, and Circulin, also Tyrocidin.
Polymyxin antibiotics inhibit bacterial membranes after binding to lipopolysaccharides (LPSs), interacting with lipid A of the outer membrane, and acting as a detergent by disrupting the membrane phospholipids, causing cellular permeability and demise.
Gramicidin and circulin are antibiotic peptides that can be incorporated into the monolayers of cell membranes.
Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria Bacillus brevis found in soil.
Polymyxin antibiotics inhibit bacterial membranes after binding to lipopolysaccharides (LPSs), interacting with lipid A of the outer membrane, and acting as a detergent by disrupting the membrane phospholipids, causing cellular permeability and demise.
Gramicidin and circulin are antibiotic peptides that can be incorporated into the monolayers of cell membranes.
Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria Bacillus brevis found in soil.
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