Interested in and clever at many things

One word substitute is Versatile.

Manicure: a cosmetic treatment of the hands involving shaping and often painting of the nails, removal of the cuticles, and softening of the skin.
Manifest: clear or obvious to the eye or mind.
Intelligent: having or showing intelligence, especially of a high level.
Versatile: able to adapt or be adapted to many different functions or activities.