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This question belongs to Competitive English Synonyms
Synonyms
?

Lost in his own revery, he forgot that vicissitudes can change the course of man's life.

Answer & Solution
Correct Answer: Option B
Difficulties : the state or condition of being difficult.
Change : make or become different.
Impediments : a hindrance or obstruction in doing something.
Unfortunate : having or marked by bad fortune; unlucky.
Vicissitudes : a change of circumstances or fortune, typically one that is unwelcome or unpleasant.

Synonym of Vicissitudes is Change
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