Examveda

Number of barr bodies is

A. One in female human beings

B. Two in female with Klinefelter syndrome

C. One in male with Klinefelter syndrome

D. All of the above

Answer: Option D

Solution (By Examveda Team)

Several Barr bodies are one in female human beings, two in a female with Klinefelter syndrome, and one in male with Klinefelter syndrome.
A Barr body or X-chromatin is an inactive X chromosome in a cell with more than one X chromosome, rendered inactive in a process called lyonization, in species with XY sex determination (including humans).
In humans with more than one X chromosome, the number of Barr bodies visible at interphase is always one fewer than the total number of X chromosomes.
In humans with euploidy, a genotypical female (46, XX karyotype) has one Barr body per somatic cell nucleus, while a genotypical male (46, XY) has none.

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