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Who gave the concept of circular chromosome in E. coli

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Correct Answer: Option A
The concept of circular chromosomes in E. coli is given by Cairns.
John Cairns demonstrated the theta structure of E. coli chromosomal replication in 1963, using an innovative method to visualize DNA replication.
The Escherichia coli chromosome is 4.6 Mb long, circular, and contains a single origin of replication. These characteristics present challenges for replication and segregation, which can nonetheless be completed as quickly as every 20 min.
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