For fatty acid synthesis, Acetyl Co-A comes from mitochondria to cytoplasm as
A. Carnitine
B. Malate
C. Citrate
D. Oxaloacetate
Answer: Option C
Solution(By Examveda Team)
For fatty acid synthesis, Acetyl Co-A comes from mitochondria to cytoplasm as Citrate.The biosynthesis of fatty acids is a multi-step process in the cytoplasm, mainly of the liver and fat cells.
Acetyl-CoA, a significant carbon input into the citric acid cycle, can be derived from glucose or fatty acids, however, a substantial portion of acetyl-CoA comes from glucose or more specifically, pyruvate. In the mitochondrial matrix, acetyl-CoA is condensed with oxaloacetate to form citrate through the action of citrate synthase in the tricarboxylic acid cycle.
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