The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is
A. Hybridization of fluorescently labelled genomic DNA from human cells to normal and cancer cell cDNA immobilized onto two glass slides
B. Hybridization of fluorescently labelled cDNAs from normaland cancer cells to a single glass slide containing immobilized clones of human genomic DNA
C. Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs
D. Hybridization of fluorescently labelled genomic DNA from normal and cancer cells to immobilized human cDNAs on a single glass slide
Answer: Option C
This Question Belongs to Biotechnology Engineering >> Bioinformatics And Biosensors
Microarray gene chips will eventually be used to
A. Screen for mutations leading to cancer
B. Identify carriers of genetic diseases
C. Identify probable behavioural traits
D. Both A and B
A. Hydrogen bonds
B. Electrostatic interaction
C. Hydrophobic interaction
D. Ester bonds
Which of the following statement is incorrect?
A. Various model organisms like mouse, yeast, nematode worm , E.coli and Arabidopsis thaliana, rice are being completely sequenced
B. It is tough to find a gene incompact genome
C. The work of developmental biologists studying model organisms, sequence data, protein structure and gene expressing data will greatly help our understanding of how organisms work at the molecular level
D. None of the above
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