Bioinformatics and Biosensors MCQ Questions & Answers

31

Luciferases can be found in bacteria, algae, fungi, jellyfish, insects, shrimp and squid and the resulting light that these organisms produce is termed

A) Luminescence B) Bioluminescence C) Fluorescence D) Electrophoresis

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Answer & Solution

Answer: Option B

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32

Match the following and select the correct answer:

Column-I	Column-II
a. UPGMA	1. Protein sequence database
b. CLUSTAL	2. Phylogenetic analysi
c. SWISS-PROT	3. 3-D structure visualization
d. Ras Mol	4. Multiple sequence alignment

A) a-2, b-4, c-1, d-3 B) a-1, b-4, c-2, d-3 C) a-4, b-1, c-2, d-3 D) a-3, b-2, c-4, d-1

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Answer & Solution

Answer: Option A

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33

The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is

A) Hybridization of fluorescently labelled genomic DNA from human cells to normal and cancer cell cDNA immobilized onto two glass slides B) Hybridization of fluorescently labelled cDNAs from normaland cancer cells to a single glass slide containing immobilized clones of human genomic DNA C) Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs D) Hybridization of fluorescently labelled genomic DNA from normal and cancer cells to immobilized human cDNAs on a single glass slide

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Answer & Solution

Answer: Option C

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34

Sequence analysis of a human gene NFI showed that a region of the protein has homology to a yeast protein called Ira. Which of the following you think is most appropriate explanation for this sequence homology?

A) The homology is of no significance B) Human and yeast are closely related C) The similarity might reflect a common function D) More information is required for making any conclusion

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Answer & Solution

Answer: Option B

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35

Which of the following is the most preferred website for searching original research articles in medicine?

A) Entrez B) Coogle C) MSN D) EMBL

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Answer & Solution

Answer: Option A

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36

Which bacterial genome was the first to be completely sequenced?

A) E. coli B) Streptococcus pneumoniae C) Haemophilus influenzae D) None of the above

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Answer & Solution

Answer: Option C

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37

Which of the following gene is most commonly found to have mutated when a cancer is detected and biosensors are used in this

A) P54 B) P53 C) P58 D) P59

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Answer & Solution

Answer: Option B

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38

Phylogeny describes a species

A) Morphological similarities with other species B) Reproductive compatibilities with other species C) Evolutionary history D) Geographic distributions

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Answer & Solution

Answer: Option C

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39

Firefly luciferase catalyzes a reaction that produces visible light in the

A) 530 - 56 nm range B) 550 - 575 nm range C) 680 - 740 nm range D) 320 - 400 nm range

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Answer & Solution

Answer: Option B

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40

An example homology and similarity tool

A) Prospect B) Emboss C) Rasmol D) BLAST

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Answer & Solution

Answer: Option D

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Bioinformatics and Biosensors MCQ Questions & Answers | Biotechnology