Immunology in Biotechnology MCQ Questions & Answers

11

Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: IgM is found in serum as a pentameric protein consisting of five IgM monomers.
Reason: The pentameric form of IgM is due to cross linking of IgM monomers via peptide bond.

A) Both (A) and (R) are true and (R) is the correct reason for (A) B) Both (A) and (R) are true but (R) is not the correct reason for (A) C) (A) is true but (R) is false D) (A) is false but (R) is true

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Answer & Solution

Answer: Option C

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12

Which one of the following is NOT a part of the human non-specific defense system?

A) Interferon B) Mucous C) Saliva D) Antibody

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Answer & Solution

Answer: Option D

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13

Match the immunoglobulin class in Group I with its properties in Group II.

Group I	Group II
P. IgG	1. Major antibody in external secretions such as bronchial mucus
Q. IgA	2. Protects against parasites
R. IgE	3. Antibody that appears first in serum after exposure to an antigen
S. IgM	4. Antibody present in highest concentration in serum

A) P-4, Q-1, R-2, S-3 B) P-3, Q-2, R-1, S-4 C) P-4, Q-3, R-1, S-2 D) P-1, Q-4, R-3, S-2

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Answer & Solution

Answer: Option A

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14

Reverse vaccinology indicates

A) From antigenic protein to vaccine development B) From antigenic polysaccharide to vaccine development C) From antibody to vaccine development D) From genome sequence to vaccine development

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Answer & Solution

Answer: Option D

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15

Viral replication within cells is inhibited by

A) IL4 B) IL1 C) IFNα D) TNFα

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Answer & Solution

Answer: Option C

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16

Antibody diversity is generated by

A) Protein splicing B) Somatic mutation C) Allelic exclusion D) Inter-chromosomal recombination

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Answer & Solution

Answer: Option D

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17

Match items in Group I with correct options from those given in Group II.

Group I	Group II
P. Tissue plasminogen activator	1. Immunomodulator
Q. Gamma interferon	2. Biodegradable plastic
R. Podophyllotoxin	3. Clot dissolution
S. Polyhydroxyalkanoate	4. Anti-tumor agent

A) P-4, Q-3, R-1, S-2 B) P-1, Q-3, R-4, S-2 C) P-3, Q-1, R-2, S-4 D) P-3, Q-1, R-4, S-2

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Answer & Solution

Answer: Option D

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18

Gram-positive bacteria are generally resistant to complement-mediated lysis because

A) Thick peptidoglycan layer prevents insertion of membrane attack complex into the inner membrane B) Gram-positive bacteria import the membrane attack complex and inactivate it C) Membrane attack complex is degraded by the proteases produced by the Gram-positive bacteria D) Gram-positive bacteria cannot activate the complement pathway

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Answer & Solution

Answer: Option A

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19

Reactions between antibodies and antigens that are detected by precipitate formation in an agar gel are referred as

A) Immunoprecipitation assay B) Immunodiffusion assay C) Immunoaggregation assay D) Immunofixation assay

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Answer & Solution

Answer: Option B

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20

Based on the heavy chain, which one of the following antibodies has multiple subtypes?

A) IgM B) IgD C) IgE D) IgG

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Answer & Solution

Answer: Option D

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Immunology in Biotechnology MCQ Questions & Answers | Biotechnology