Molecular Biology and Genetics MCQ Questions & Answers | Biotechnology

In nature, the horizontal gene transfer across bacteria is mediated by

In tomato plant, red (R) is dominant over yellow (r) for fruit color and purple (P) is dominant over green (p) for stem color. Fruit color and stem color assort independently. The number of progeny plants of different fruit/stem colors obtained from a mating are as follows:
Red fruit, purple stem - 145
Red fruit, green stem - 184
Yellow fruit, purple stem - 66
Yellow fruit, green stem - 47
What are the genotypes of the parent plants in this mating?

Which one of the following covalent linkages exists between 7-Methyl guanosine (m7G) and mRNAs?

siRNA(s) interfere at

Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Isopropylthiogalactoside (IPTG) is a gratuitous inducer of lactose operon.
Reason: Gratuitous inducers are chemical analogs which behave like natural inducer but they do not serve as substrate for the enzymes that are subsequently synthesized.

Hypophosphatemia is manifested by an X-linked dominant allele. What proportion of the offspring from a normal male and an affected heterozygous female will manifest the disease?

Match the classes of RNA molecules in Group I with their functions in Group II.

Group I	Group II
P. snoRNA	1. Protects germline from transposable elements
Q. piRNA	2. Blocks translation of selected mRNA
R. miRNA	3. Template for telomere elongation
S. snRNA	4. Modification and processing of rRNA
	5. Splicing of RNA transcripts

Reverse genetics means

The cellular process which utilizes RNA-induced silencing complex to block gene expression is

Match the type of chromosomal inheritance (Column I) with the corresponding genetic disease or trait (Column II).

Column I	Column II
P. Autosomal recessive inheritance	1. Huntington disease
Q. Autosomal dominant inheritance	2. Hairy ears
R. X-linked inheritance	3. Cystic fibrosis
S. Y-linked inheritance	4. Hemophilia