Molecular Biology and Genetics MCQ Questions & Answers | Biotechnology

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11.
5' capping of mRNA transcripts in eukaryotes involves, the following events:
P. Addition of GMP on the 5' end.
Q. Removal of γ-phosphate of the triphosphate on first base at the 5' end.
R. 5' - 5' linkage between GMP and the first base at 5' end.
S. Addition of methyl group to N7 position of guanine.
Which one of the following is the correct sequence of events?

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12.
Determine the correctness of the following statements.
I. Enhancer sequences are those DNA sequences that are involved in increasing the rate of DNA replication.
II. Enhancer sequences work by binding with eukaryotic gene activator factors.

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14.
For their efficient translation, eubacterial mRNAs possess a Shine-Dalgarno sequence for its recognition by an anti-Shine-Dalgarno sequence (ASD) in the ribosomes. The correct statement is

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17.
A DNA sequence, 5'-ATGGACGTGCTTCCCAAAG-CATCGGGC-3', is mutated to obtain
P. 5'- ATGGACGTGCTTCaCAAAGCATCGGGC -3'
Q. 5'- ATGGACGTGCTTCCCgAAAGCATCGGGC -3'
R. 5'- ATGGACGTGCTTCC-AAAGCATCGGGC -3'
S. 5'- ATGGACGTGCTTCCCAAtGCATCGGGC -3'
T. 5'- ATGGACGaGCTTCCCAAAGCATCGGGC -3'
[Point mutations are shown in the lower case or '-' within the sequences]
Which of the above mutant sequences do not have frameshift?

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20.
In a relatively large but finite and closed population of sexually reproducing diploid organisms, the frequency of homozygous genotype PP changes from 0.40 to 0.50 and that of pp changes from 0.40 to 0.41 in a span of 10 generations. Which of the following is the most likely cause for the above change in frequency of the PP genotype?

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