Molecular Biology and Genetics MCQ Questions & Answers

1.
RNA is very much susceptible to hydrolysis in alkali because

A. It contains uracil residues in its structure

B. its 2'-OH group participate in intramolecular cleavage of phosphodiester backbone

C. Cleavage occurs in the glycosylic bonds of purine bases

D. Cleavage occurs in the glycosylic bonds of pyrimidine bases

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2.
Rho-dependent and rho-independent transcription termination mechanisms operate in prokaryotes. Rho independent termination mechanism involves

A. Binding of the rho protein upstream of the termination element

B. No protein factors and only RNA secondary structure and run of 'U's

C. Presence of UGA or UAA stop codons

D. Binding of accessory factors at termination signal

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3.
Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Cytoplasmic male sterility (cms) is invariably due to defect(s) in mitochondrial function.
Reason: cms can be overcome by pollinating a fertility restoring (Rf ) plant with pollen from a non cms plant.

A. Both (A) and (R) are true and (R) is the correct reason for (A)

B. Both (A) and (R) are true and (R) is not the correct reason for (A)

C. (A) is false but (R) is true

D. (A) is true but (R) is false

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4.
Mobile genetic elements present in human genome are
P. Long interspersed elements (LINEs)
Q. Short interspersed elements (SINEs)
R. P elements
S. IS elements

A. Q, R

B. P, Q

C. P, R

D. Q, S

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5.
The direction of shell coiling in the snail Limnaea peregra is a classic example of

A. Chromosomal inheritance

B. Extra-chromosomal inheritance

C. Chromosomal translocation

D. Homologous recombination

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6.
Which of the following characteristics with respect to bacterial DNA polymerase III are true?
P. Initiation of chain synthesis
Q. 5' → 3' polymerization
R. 3' → 5' exonuclease activity
S. 5' → 3' exonuclease activity

A. P and Q only

B. Q and R only

C. Q and S only

D. P and S only

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7.
The protein in eukaryotes which is subjected to degradation undergoes

A. Phosphorylation

B. Carboxylation

C. Ubiquitation

D. Methylation

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8.
In mismatch correction repair, the parental DNA strand is distinguished from the daughter strand by

A. Acetylation

B. Phosphorylation

C. Methylation

D. Glycosylation

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9.
Which one of the following is coded by the ABO blood group locus in the human genome?

A. Acyl transferase

B. Galactosyltransferase

C. Transposase

D. β-Galactosidase

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10.
Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: The association constant in water for the G-C base pair is three times lower than that for the A-T base pair.
Reason: There are three hydrogen bonds in the G-C base pair and two in the A-T base pair.

A. Both (A) and (R) are true and (R) is the correct reason for (A)

B. (A) is false, but (R) is true

C. Both (A) and (R) are false

D. Both (A) and (R) are true and (R) is not the correct reason for (A)

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Molecular Biology and Genetics MCQ Questions & Answers | Biotechnology

1. RNA is very much susceptible to hydrolysis in alkali because

Answer & Solution

2. Rho-dependent and rho-independent transcription termination mechanisms operate in prokaryotes. Rho independent termination mechanism involves

Answer & Solution

Answer & Solution

4. Mobile genetic elements present in human genome are P. Long interspersed elements (LINEs) Q. Short interspersed elements (SINEs) R. P elements S. IS elements

Answer & Solution

5. The direction of shell coiling in the snail Limnaea peregra is a classic example of

Answer & Solution

6. Which of the following characteristics with respect to bacterial DNA polymerase III are true? P. Initiation of chain synthesis Q. 5' → 3' polymerization R. 3' → 5' exonuclease activity S. 5' → 3' exonuclease activity

Answer & Solution

7. The protein in eukaryotes which is subjected to degradation undergoes

Answer & Solution

8. In mismatch correction repair, the parental DNA strand is distinguished from the daughter strand by

Answer & Solution

9. Which one of the following is coded by the ABO blood group locus in the human genome?

Answer & Solution

Answer & Solution

1.
RNA is very much susceptible to hydrolysis in alkali because

2.
Rho-dependent and rho-independent transcription termination mechanisms operate in prokaryotes. Rho independent termination mechanism involves

4.
Mobile genetic elements present in human genome are
P. Long interspersed elements (LINEs)
Q. Short interspersed elements (SINEs)
R. P elements
S. IS elements

5.
The direction of shell coiling in the snail Limnaea peregra is a classic example of

6.
Which of the following characteristics with respect to bacterial DNA polymerase III are true?
P. Initiation of chain synthesis
Q. 5' → 3' polymerization
R. 3' → 5' exonuclease activity
S. 5' → 3' exonuclease activity

7.
The protein in eukaryotes which is subjected to degradation undergoes

8.
In mismatch correction repair, the parental DNA strand is distinguished from the daughter strand by

9.
Which one of the following is coded by the ABO blood group locus in the human genome?