Molecular Biology and Genetics MCQ Questions & Answers

1

RNA is very much susceptible to hydrolysis in alkali because

A) It contains uracil residues in its structure B) its 2'-OH group participate in intramolecular cleavage of phosphodiester backbone C) Cleavage occurs in the glycosylic bonds of purine bases D) Cleavage occurs in the glycosylic bonds of pyrimidine bases

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Answer & Solution

Answer: Option B

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2

Rho-dependent and rho-independent transcription termination mechanisms operate in prokaryotes. Rho independent termination mechanism involves

A) Binding of the rho protein upstream of the termination element B) No protein factors and only RNA secondary structure and run of 'U's C) Presence of UGA or UAA stop codons D) Binding of accessory factors at termination signal

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Answer & Solution

Answer: Option B

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3

Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: Cytoplasmic male sterility (cms) is invariably due to defect(s) in mitochondrial function.
Reason: cms can be overcome by pollinating a fertility restoring (Rf ) plant with pollen from a non cms plant.

A) Both (A) and (R) are true and (R) is the correct reason for (A) B) Both (A) and (R) are true and (R) is not the correct reason for (A) C) (A) is false but (R) is true D) (A) is true but (R) is false

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Answer & Solution

Answer: Option A

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4

Mobile genetic elements present in human genome are
P. Long interspersed elements (LINEs)
Q. Short interspersed elements (SINEs)
R. P elements
S. IS elements

A) Q, R B) P, Q C) P, R D) Q, S

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Answer & Solution

Answer: Option B

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5

The direction of shell coiling in the snail Limnaea peregra is a classic example of

A) Chromosomal inheritance B) Extra-chromosomal inheritance C) Chromosomal translocation D) Homologous recombination

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Answer & Solution

Answer: Option B

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6

Which of the following characteristics with respect to bacterial DNA polymerase III are true?
P. Initiation of chain synthesis
Q. 5' → 3' polymerization
R. 3' → 5' exonuclease activity
S. 5' → 3' exonuclease activity

A) P and Q only B) Q and R only C) Q and S only D) P and S only

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Answer & Solution

Answer: Option B

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7

The protein in eukaryotes which is subjected to degradation undergoes

A) Phosphorylation B) Carboxylation C) Ubiquitation D) Methylation

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Answer & Solution

Answer: Option C

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8

In mismatch correction repair, the parental DNA strand is distinguished from the daughter strand by

A) Acetylation B) Phosphorylation C) Methylation D) Glycosylation

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Answer & Solution

Answer: Option C

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9

Which one of the following is coded by the ABO blood group locus in the human genome?

A) Acyl transferase B) Galactosyltransferase C) Transposase D) β-Galactosidase

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Answer & Solution

Answer: Option B

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10

Determine the correctness or otherwise of the following Assertion (A) and the Reason (R).
Assertion: The association constant in water for the G-C base pair is three times lower than that for the A-T base pair.
Reason: There are three hydrogen bonds in the G-C base pair and two in the A-T base pair.

A) Both (A) and (R) are true and (R) is the correct reason for (A) B) (A) is false, but (R) is true C) Both (A) and (R) are false D) Both (A) and (R) are true and (R) is not the correct reason for (A)

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Answer & Solution

Answer: Option B

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Molecular Biology and Genetics MCQ Questions & Answers | Biotechnology