Match the entries in the Group I with the entries in Group II.

Group I	Group II
P. Threading	1. Gene duplication
Q. FASTA	2. Fold prediction
R. Profile	3. HMM
S. Paralogs	4. k-tuple

A. P-2, Q-1, R-3, S-4

B. P-2, Q-4, R-3, S-1

C. P-3, Q-4, R-2, S-1

D. P-1, Q-4, R-3, S-2

Answer: Option B